We develop microreactor and continuous-flow strategies for sustainable chemical and pharmaceutical production — from biodiesel synthesis with integrated continuous purification and life-cycle assessment (LCA), to the full-flow production of pharmaceutical compounds such as acetylsalicylic acid. Our microreactor work on sustainable biodiesel was selected as the Outside Front Cover story of Green Chemistry (2025).

We apply machine learning to fluidic and bioprocess problems — from predicting two-phase flow separation at liquid–liquid interfaces, to unsupervised cell classification for biohydrogen production prediction.

By tuning helix-structure heights to manipulate bubble departure, we enhance pool boiling heat transfer performance — a passive route to more efficient thermal management.

We investigate two-phase flow behaviour across different gravity environments, aiming for fluid-handling and extraction technologies that work in space. Our team has taken part in microgravity experiments, including drop-tower campaigns in Bremen, Germany.

We study the biomechanics of nature's sniffers, combining flow visualisation with engineering design to reveal the multi-scale fluid dynamics inside the nasal cavity and to answer biological questions about somatotopic odour maps. In collaboration with Prof. Wang and Prof. Chi (Physics, NCHU) and Prof. Jeng-Horng Chen (NCKU).

We demonstrated a pump-free microfluidic device that uses osmotic pressure to drive and modulate flow, removing the need for external pumps and tubing. The platform also enables on-chip single-cell trapping for biomedical applications.

We build a microfluidic blood–brain barrier (BBB) model with built-in flow that combines the strengths of in vitro and in vivo systems. It offers a rapid, animal-free tool for screening the permeability of nanoparticles and therapeutics across the neuroprotective barrier.

An AI project with Taiwan's Directorate General of Highways: we develop automated animal recognition and acoustic–optical slow-down systems that detect leopard cats near roads and reduce roadkill along central Taiwan's wildlife-friendly roads.